Dr. Brown's Natural Flow baby bottle was invented by a doctor and tested on his own children when they were babies, so you can rest assured that this product is as safe as it is effective. This revolutionary baby bottle features a patented "no vacuum" design. It helps colicky babies settle down/sleep and reduces colic, spit-up, burping and gas. This also helps to prevent fluid in the ear/no vacuum. It is easy to clean, and dishwasher safe. Includes 3-8 ounce Wide Neck Bottles;2-4 ounce Wide Neck Bottles;2-Extra Level 2 Nipples;2-Storage/Travel Caps;3-Cleaning Brushes, BPA free