Neonatal surgeon Addison Montgomery escapes from a dysfunctional love triangle, leaving her friends and foes at Seattle Grace Hospital behind for a fresh start in Los Angeles, where she joins a trendy public clinic run by her recently divorced friends, Sam and Naomi Bennett.

Work lives and personal lives combine as these doctors deal with the pressures of both worlds. Intense episodes that deal with the stressful world of medicine and health scares. Addison wants a fresh start and she's getting more then she bargained for when she joins this trendy public clinic.